خصوصیات ویرولوژیک بیماران مبتلا به عفونت مزمن هپاتیت B

 Background used to determine prognosis of hepatitis B. The present study was conducted to determine the virologic characteristics of chronic hepatitis B in a group of Iranian patients .  Materials and methods were selected. They had positive HBsAg for at least 6 months. Complementary laboratory tests were achieved as follow: liver function tests, HBeAg, HBeAb , HBcAb and HBsAb. Liver biopsy was performed if indicated .  Results were HBeAg positive as compared to 77 who were HBeAg negative. Four patients had concurrent HCVAb and HBsAg. HBsAb was positive in 5 patients. HBeAg was positive in 13 (26%) females and 32 (33%) males (NS).  Results have revealed that HBeAg was correlated with chronic hepatitis B (p<0.001 ).  Conclusion introduction of DNA assay for definite diagnosis .